Talk from Frédérique Liegeois,PhD – UCL - Great Ormond Street Institute of Child Health, London UK
Short abstract:
A large proportion of children with neurodevelopmental disorders have more than one diagnosis. For instance, there is high co-occurrence of developmental coordination disorder (DCD) and childhood apraxia of speech (CAS), CAS and language disorder, DCD and attention deficits. The brain basis of this overlap is poorly understood, and individual variability remains difficult to predict.
Here I will present work that used structural MRI to identify the brain correlates of CAS and DCD in school-aged children. We used tractography reconstruction from diffusion-weighted datasets as well as volumetric and cortical morphometry methods. This body of work identified subtle grey and white matter differences impacting shared but also distinct networks.