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The François Jacob Institute of Biology brings together five departments and three services
The last two years in scientific news
Preclinical trials carried out as part of a CEA-Irig–CEA-Jacob partnership have shown that a spike-protein-based candidate vaccine provides complete protection against SARS-CoV-2 infection.
Researchers from IRCM furnish initial information on the mechanisms regulating DNA double-strand break repair in yeast heterochromatin. Sir3 plays an essential role in the choice of a repair pathway.
An international team with researchers from the CEA (Genoscope, CEA-Jacob) has produced a dataset of the deep ocean floor and compared it to the other oceanic realms at a worldwide scale. The results, published in the in Science Advances, show that the deep oceanic floor is home to a mostly unknown biodiversity largely superior to that of plankton.
In a study published in Viruses, a team of researchers from SRHI and the University of Ferrara (Italy) showed that the soluble form of HLA-G may contribute significant anti-inflammatory properties via its role in controlling the adhesion of neutrophils to endothelial cells and thus improve disease outcome in patients with COVID-19.
In a study published in Cancer Letters, SRHI's researchers (CEA-Jacob) highlight the therapeutic value of targeting the HLA-G/IL2 immune checkpoint in clear cell renal cell carcinoma.
In a study published in Science of the Total Environment, researchers from SIMoS (DMTS/CEA-Joliot), in collaboration with the Faculty of Pharmacy of Paris and MIRCen (CEA-Jacob) have shown for the first time in an animal model the capacity of Pinnatoxin-G, a marine neurotoxin, to cross physiological barriers to reach its molecular targets.
In a review published in Cell Metabolism, Gilles Bonvento (LMN/MIRCen/CEA-Jacob) and Juan P. Bolaños (IBFG/University of Salamanca) present the latest findings on astrocyte-neuron metabolic cooperation and how it affects brain function.
Dans le cadre d'une collaboration internationale, les chercheurs du Genoscope mettent en lumière de nouveaux organismes diazotrophes grâce aux données moléculaires et d'imagerie collectées par la goélette scientifique Tara entre 2009 et 2013.
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.