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To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
All the news of the Institute of life sciences Frédéric Joliot
The Neuro2Co project, led by INRA Val de Loire whose NeuroSpin is a partner, aims to test the hypothesis according to which the organization of brain connections, the connectome, accounts for behavioral adaptation strategies of different animal species. Under the impetus of this project, 3 science teachers from the secondary-school André Bauchant (37) animate since September 2017 a scientific workshop, the workshop Ciboulot, for students from 5th to 3rd. It is in this context that they came to NeuroSpin on June 12, hosted by Cyril Poupon and his team to achieve the acquisition of images in MRI of a quail brain.
A SPI Research Team (LI2D, Marcoule), in collaboration with CIRAD and AU-PANVAC, proposes a new quality control technique for veterinary vaccines, based on very high resolution mass spectrometry. This strategy, based on the use of an ad hoc database to measure the proportion of antigens and contaminants in the vaccine preparation, will improve the quality control of vaccines against contagious caprine pleuropneumonia.
IMIV unit (SHFJ), in collaboration with the Gustave Roussy Institute, has developed the free software platform LIFEx that allows to characterize the tumor heterogeneity from any type of medical images: PET, MRI, scanner, ultrasound. With nearly 900 members, this platform has an international success because it facilitates the realization of radiomic studies, conducted in the context of personalized medicine.
Several teams from the Frédéric Joliot Institute took part in the sports event of the Paris-Saclay centre on June 22, 2018, a moment placed under the sign of conviviality and good humor. And some of them even won prizes ...
An I2BC Research Team, in collaboration with the ICSN and the Ecole Polytechnique, has mapped for the first time, in man and the model plant Arabidopsis thaliana, the myristoylome, namely the whole proteins modified with a fatty acid, myristate. This modification is important because it targets these proteins to the membranes and thus contributes to their subcellular compartmentalization. These data represent an important resource, available to the community of biologists.
A SCBM Research Team, in collaboration with SHFJ, SIMOPRO and Karolinska Institute, has discovered a method inspired by the "click" chemistry which, from radioactive carbon dioxide, can synthesize in just five minutes radiolabeled molecules containing a cyclic urea moiety. This method has been used for the ultra-rapid isotope labeling of drugs, without modification of their structure and with an unequaled efficiency.
On the 7th and 8th of June were held the second edition of the PhD Days (JDD) of the Frédéric Joliot Institute for Life Sciences. In the spirit of previous days, PhD students and researchers met during four half-days to discuss about their work, but also to discover the diversity of topics addressed in our institute and expand their own knowledge.
Being part of an international consortium, the Neurofunctional Imaging Group (NeuroSpin, Bordeaux) and the Max Planck Institute for Psycholinguinstics have characterized the asymmetries of surface and thickness of the cerebral cortex of 17,141 individuals from MRI. This study published in PNAS, the largest ever done, provides a unique reference for studying the genetic basis of cerebral asymmetries and the alteration of lateralization during cognitive, neurological and psychiatric disorders.
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.