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target for phagocytosis-mediated cellular immunotherapy in acute leukemia. | Allouch A, Voisin L, Zhang Y, Syed R, Lecluse Y, Calvo J, Sélimoglu-Buet D, De Botton S, Louache F, Pflumio F, Solary E, Perfettini JL | | | | | Concurrent CDX2 cis-deregulation and UBTF-ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL. | Passet M, Kim R, Gachet S, Sigaux F, Chaumeil J, Galland A, Sexton T, Quentin S, Hernandez L, Larcher L, Bergugnat H, Ye T, Karasu N, Caye-Eude A, Heizmann B, Duluc I, Chevallier P, Rousselot P, Huguet F, Leguay TT, Hunault-Berger MM, Pflumio F, Freund JN, Lobry C, Lheritier V, Dombret H, Domon-Dell C, Soulier J, Boissel N, Clappier E | | | | | High caspase 3 and vulnerability to dual BCL2 family inhibition define ETO2::GLIS2 pediatric leukemia. | Aid Z, Robert E, Lopez CK, Bourgoin M, Boudia F, Le Mene M, Riviere J, Baille M, Benbarche S, Renou L, Fagnan A, Thirant C, Federici L, Touchard L, Lecluse Y, Jetten A, Geoerger B, Lapillonne H, Solary E, Gaudry M, Meshinchi S, Pflumio F, Auberger P, Lobry C, Petit A, Jacquel A, Mercher T | | | | | REDD1 is a gatekeeper of murine hematopoietic stem cell functions during stress responses. | Barroca V, Henry E, Dechamps N, Renou L, Chaintreuil P, Kulkarni R, Devanand S, Jacquel A, Robert G, Auberger P, Pflumio F, Arcangeli ML | | | | | A DL-4- and TNF?-based culture system to generate high numbers of nonmodified or genetically modified immunotherapeutic human T-lymphoid progenitors. | Moirangthem RD, Ma K, Lizot S, Cordesse A, Olivré J, de Chappedelaine C, Joshi A, Cieslak A, Tchen J, Cagnard N, Asnafi V, Rausell A, Simons L, Zuber J, Taghon T, Staal FJT, Pflumio F, Six E, Cavazzana M, Lagresle-Peyrou C, Soheili T, André I | | | | | How Hematopoietic Stem Cells Respond to Irradiation: Similarities and Differences between Low and High Doses of Ionizing Radiations | | | | | | JAM-C/Jam-C Expression Is Primarily Expressed in Mouse Hematopoietic Stem Cells. | Henry E, Barroca V, Lopez CK, Aurrand-Lions M, Lewandowski D, Mercher T, Arcangeli ML | | | | | Hypoxia favors chemoresistance in T-ALL through a HIF1-mediated mTORC1 inhibition loop | L Fahy, J Calvo, S Chabi, L Renou, C Le Maout, S Poglio, T Leblanc, A Petit, A Baruchel, P Ballerini, I Naguibneva, R Haddad, ML Arcangeli, F Mazurier, F Pflumio* and B Uzan | | | | | Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers. | Fagnan A, Bagger FO, Piqué-Borràs MR, Ignacimouttou C, Caulier A, Lopez C, Robert E, Uzan B, Gelsi-Boyer V, Aid Z, Thirant C, Moll U, Tauchmann S, Kurtovic-Kozaric A, Maciejewski JP, Dierks C, Spinelli O, Salmoiraghi S, Pabst T, Shimoda K, Deleuze V, Lapillonne H, Sweeney C, Mansat-De Mas V, Leite B, Kadri Z, Malinge S, de Botton S, Micol JB, Kile BT, Carmichael CL, Iacobucci I, Mullighan CG, Carroll MP, Valent P, Bernard OA, Delabesse E, Vyas P, Birnbaum D, Anguita E, Garcon L, Soler E, Schwaller J, Mercher T | | | | | Combined G-CSF and Plerixafor enhance hematopoietic recovery of CD34+ cells from poor mobilizer patients in NSG mice. | Arcangeli ML, Brault P, Bourhis JH, Kuhnowski F, Henry E, Barroca V et al. | | | | | Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia. | Zhou Y, Han C, Wang E, Lorch AH, Serafin V, Cho B-K et al. | | | | | Ultra-high dose rate FLASH and conventional dose rate irradiation differentially affect human acute lymphoblastic leukemia and normal hematopoiesis. | Chabi S, Hong Van To T, Leavitt R, PhD4, Poglio S, Gonçalves Jorge P , Jaccard M, PeterssonK, Petit B, Roméo, PH, Pflumio,F, Vozenin, MC and Uzan, B | | | | | Human hematopoietic stem/progenitor cells display reactive oxygen species-dependent long-term hematopoietic defects after exposure to low doses of ionizing radiations | Elia Henry, Inès Souissi-Sahraoui, Margaux Deynoux, Andréas Lefèvre, Vilma Barroca, Anna Campalans, Véronique Ménard, Julien Calvo, Françoise Pflumio, Marie-Laure Arcangeli | | | | | Desperately seeking a home marrow niche for T-cell acute lymphoblastic leukaemia. | Calvo J, Fahy L, Uzan B, Pflumio F. | | | | | A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation. | Roos-Weil D, Decaudin C, Armand M, Della-Valle V, Diop MK, Ghamlouch H, Ropars V, Hérate C, Lara D, Durot E, Haddad R, Mylonas E, Damm F, Pflumio F, Stoilova B, Metzner M, Elemento O, Dessen P, Camara-Clayette V, Cosset F-L, et al | | | | | Frontline Science: Exhaustion and senescence marker profiles on human T cells in BRGSF-A2 humanized mice resemble those in human samples. | Labarthe L, Henriquez S, Lambotte O, Di Santo JP, Le Grand R, Pflumio F, Arcangeli M-L, Legrand N & Bourgeois C | | | | | Hypoxia Regulates Lymphoid Development of Human Hematopoietic Progenitors. | Chabi S, Uzan B, Naguibneva I, Rucci J, Fahy L, Calvo J, Arcangeli M-L, Mazurier F, Pflumio F & Haddad R | | | | | Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia. | Lopez CK, Noguera E, Stavropoulou V, Robert E, Aid Z, Ballerini P, Bilhou-Nabera C, Lapillonne H, Boudia F, Thirant C, Fagnan A, Arcangeli M-L, Kinston SJ, Diop M, Job B, Lecluse Y, Brunet E, Babin L, Villeval JL, Delabesse E, et al | | | | | T-cell acute lymphoblastic leukemia displays autocrine production of Interleukin-7. | Buffière A, Uzan B, Aucagne R, Hermetet F, Mas M, Nassurdine S, Aznague A, Carmignac V, Tournier B, Bouchot O, Ballerini P, Barata J-T, Bastie J-N, Delva L, Pflumio F, Quéré R | | | | | Epigenetic silencing affects L-asparaginase sensitivity and predicts outcome in T-ALL | Touzart A, Lengline E, Latiri M, Belhocine M, Smith C, Thomas X, Spicuglia S, Puthier D, Pflumio F, Leguay T, Graux C, Chalandon Y, Huguet F, Leprêtre S, Ifrah N, Dombret H, Macintyre E, Hunault-Berger M, Boissel N, Asnafi V. | | | | | Saracatinib impairs maintenance of human T-ALL by targeting the LCK tyrosine kinase in cells displaying high level of lipid rafts. | Buffière A, Accogli T, Saint-Paul L, Lucchi G, Uzan B, Ballerini P, Bastie J-N, Delva L, Pflumio F, Quéré R | | | | | Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells | Karamitros D, Stoilova B, Aboukhalil Z, Hamey F, Reinisch A, Samitsch M, Quek L, Otto G, Repapi E, Doondeea J, Usukhbayar B, Calvo J, Taylor S, Goardon N, Six E, Pflumio F, Porcher C, Majeti R, Gottgens B, Vyas P | | | | | Bone marrow sites differently imprint dormancy and chemoresistance to T-cell acute lymphoblastic leukemia | Cahu X, Calvo J, Poglio S, Prade N, Colsch B, Arcangeli ML, Leblanc T, Petit A, Baleydier F, Baruchel A, Landman-Parker J, Junot C, Larghero J, Ballerini P, Delabesse E, Uzan B, Pflumio F | | | | | Bone Marrow Hematons: An Access Point to the Human Hematopoietic Niche | Janel A, Berger J, Bourgne C, Lemal R, Boiret-Dupre N, Dubois-Galopin F, Dechelotte P, Bothorel C, Hermet E, Chabi S, Bay JO, Lambert C, Pereira B, Pflumio F, Haddad R, Berger MG | | | | | ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia | Thirant C, Ignacimouttou C, Lopez CK, Diop M, Le Mouel L, Thiollier C, Siret A, Dessen P, Aid Z, Riviere J, Rameau P, Lefebvre C, Khaled M, Leverger G, Ballerini P, Petit A, Raslova H, Carmichael CL, Kile BT, Soler E, Crispino JD, Wichmann C, Pflumio F, Schwaller J, Vainchenker W, Lobry C, Droin N, Bernard OA, Malinge S, Mercher T | | | | | Homeobox protein TLX3 activates miR-125b expression to promote T-cell acute lymphoblastic leukemia | Renou L, Boelle PY, Deswarte C, Spicuglia S, Benyoucef A, Calvo J, Uzan B, Belhocine M, Cieslak A, Landman-Parker J, Baruchel A, Asnafi V, Pflumio F, Ballerini P, Naguibneva I | | | | | PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells | Naudin C, Hattabi A, Michelet F, Miri-Nezhad A, Benyoucef A, Pflumio F, Guillonneau F, Fichelson S, Vigon I, Dusanter-Fourt I, Lauret E | | |
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