 | | The integrity of the FOG-2 LXCXE pRb-binding motif is required for small intestine homeostasis. | Goupille O, Kadri Z, Langelé A, Luccantoni S, Badoual C, Leboulch P, Chrétien S. | | | | | Enhanced Transduction of Macaca fascicularis Hematopoietic Cells with Chimeric Lentiviral Vectors. | Sii-Felice K, Castillo Padilla J, Relouzat F, Cheuzeville J, Tantawet S, Maouche L, Le Grand R, Leboulch P, Payen E4. | | | | | UM171 Enhances Lentiviral Gene Transfer and Recovery of Primitive Human Hematopoietic Cells. | Ngom M, Imren S, Maetzig T, Adair JE, Knapp DJHF, Chagraoui J, Fares I, Bordeleau ME, Sauvageau G, Leboulch P, Eaves C, Humphries RK. | | | | | Hemoglobin disorders: lentiviral gene therapy in the starting blocks to enter clinical practice. | Sii-Felice K, Giorgi M, Leboulch P, Payen E. | | | | | Gene Therapy in Patients with Transfusion-Dependent Beta-Thalassemia | Thompson AA, Walters MC, Kwiatkowski J, Rasko JEJ, Ribeil JA, Hongeng S, Magrin E, Schiller GJ, Payen E, Semeraro M, Moshous D, Lefrere F, Puy H, Bourget P, Magnani A, Caccavelli L, Diana JS, Suarez F, Monpoux F, Brousse V, Poirot C, Brouzes C, Meritet JF, Pondarré C, Beuzard Y, Chrétien S, Lefebvre T, Teachey DT, Anurathapan U, Ho PJ, von Kalle C, Kletzel M, Vichinsky E, Soni S, Veres G, Negre O, Ross RW, Davidson D, Petrusich A, Sandler L, Asmal M, Hermine O, De Montalembert M, Hacein-Bey-Abina S, Blanche S, Leboulch P, Cavazzana M | | | | | Ex Vivo Selection of Transduced Hematopoietic Stem Cells for Gene Therapy of beta-Hemoglobinopathies | Bhukhai K, de Dreuzy E, Giorgi M, Colomb C, Negre O, Denaro M, Gillet-Legrand B, Cheuzeville J, Paulard A, Trebeden-Negre H, Borwornpinyo S, Sii-Felice K, Maouche L, Down JD, Leboulch P, Payen E. | | | | | The LXCXE Retinoblastoma Protein-Binding Motif of FOG-2 Regulates Adipogenesis. | Goupille O., Penglong T., Kadri Z., Granger-Locatelli M., Badoual C. Fucharoen S., Maouche-Chrétien L., Leboulch P., and Chrétien S. | | | | | Induced pluripotent stem cell generation from a man carrying a complex chromosomal rearrangement as a genetic model for infertility studies | Mouka A, Izard V, Tachdjian G, Brisset S, Yates F, Mayeur A, Drevillon L, Jarray R, Leboulch P, Maouche-Chretien L, Tosca L | | | | | Gene Therapy in a Patient with Sickle Cell Disease | Ribeil JA, Hacein-Bey-Abina S, Payen E, Magnani A, Semeraro M, Magrin E, Caccavelli L, Neven B, Bourget P, El Nemer W, Bartolucci P, Weber L, Puy H, Meritet JF, Grevent D, Beuzard Y, Chretien S, Lefebvre T, Ross RW, Negre O, Veres G, Sandler L, Soni S, de Montalembert M, Blanche S, Leboulch P, Cavazzana M | | | | | Gene Therapy in a Patient with Sickle Cell Disease REPLY | | | | | | Inhibition of the acetyl lysine-binding pocket of bromodomain and extraterminal domain proteins interferes with adipogenesis | Goupille O, Penglong T, Kadri Z, Granger-Locatelli M, Fucharoen S, Maouche-Chretien L, Prost S, Leboulch P, Chretien S. | | | | | Gene Therapy of the beta-Hemoglobinopathies by Lentiviral Transfer of the beta(A(T87Q))-Globin Gene | Negre O, Eggimann AV, Beuzard Y, Ribeil JA, Bourget P, Borwornpinyo S, Hongeng S, Hacein-Bey S, Cavazzana M, Leboulch P, Payen E | | | | | High-Efficiency Transduction of Primary Human Hematopoietic Stem/Progenitor Cells by AAV6 Vectors: Strategies for Overcoming Donor-Variation and Implications in Genome Editing | Ling C, Bhukhai K, Yin ZF, Tan MQ, Yoder MC, Leboulch P, Payen E, Srivastava A | | | | | Preclinical Evaluation of Efficacy and Safety of an Improved Lentiviral Vector for the Treatment of beta-Thalassemia and Sickle Cell Disease | Negre O, Bartholomae C, Beuzard Y, Cavazzana M, Christiansen L, Courne C, Deichmann A, Denaro M, De Dreuzy E, Finer M, Fronza R, Gillet-Legrand B, Joubert C, Kutner R, Leboulch P, Maouche L, Paulard A, Pierciey FJ, Rothe M, Ryu B, Schmidt M, von Kalle C, Payen E, Veres G | | | | | Erosion of the chronic myeloid leukaemia stem cell pool by PPAR gamma agonists | Prost S, Relouzat F, Spentchian M, Ouzegdouh Y, Saliba J, Massonnet G, Beressi JP, Verhoeyen E, Raggueneau V, Maneglier B, Castaigne S, Chomienne C, Chretien S, Rousselot P, Leboulch P | | | | | Transplantation of Macaca cynomolgus iPS-derived hematopoietic cells in NSG immunodeficient mice | Abed S, Tubsuwan A, Chaichompoo P, Park IH, Pailleret A, Benyoucef A, Tosca L, De Dreuzy E, Paulard A, Granger-Locatelli M, Relouzat F, Prost S, Tachdjian G, Fucharoen S, Daley GQ, Payen E, Chretien S, Leboulch P, Maouche-Chretien L | | | | | Erythropoietin and IGF-1 signaling synchronize cell proliferation and maturation during erythropoiesis | Kadri Z, Lefevre C, Goupille O, Penglong T, Granger-Locatelli M, Fucharoen S, Maouche-Chretien L, Leboulch P, Chretien S | | | | | Loss of Major Molecular Response As a Trigger for Restarting Tyrosine Kinase Inhibitor Therapy in Patients With Chronic-Phase Chronic Myelogenous Leukemia Who Have Stopped Imatinib After Durable Undetectable Disease | Rousselot P, Charbonnier A, Cony-Makhoul P, Agape P, Nicolini FE, Varet B, Gardembas M, Etienne G, Rea D, Roy L, Escoffre-Barbe M, Guerci-Bresler A, Tulliez M, Prost S, Spentchian M, Cayuela JM, Reiffers J, Chomel JC, Turhan A, Guilhot J, Guilhot F, Mahon FX | | | | | An activin receptor IIA ligand trap corrects ineffective erythropoiesis in beta-thalassemia | Dussiot M, Maciel TT, Fricot A, Chartier C, Negre O, Veiga J, Grapton D, Paubelle E, Payen E, Beuzard Y, Leboulch P, Ribeil JA, Arlet JB, Cote F, Courtois G, Ginzburg YZ, Daniel TO, Chopra R, Sung V, Hermine O, Moura IC | | | | | HSP70 sequestration by free alpha-globin promotes ineffective erythropoiesis in beta-thalassaemia | Arlet JB, Ribeil JA, Guillem F, Negre O, Hazoume A, Marcion G, Beuzard Y, Dussiot M, Moura IC, Demarest S, de Beauchene IC, Belaid-Choucair Z, Sevin M, Maciel TT, Auclair C, Leboulch P, Chretien S, Tchertanov L, Baudin-Creuza V, Seigneuric R, Fontenay M, Garrido C, Hermine O, Courtois G | | | | | C-Type Lectin-like Receptor LOX-1 Promotes Dendritic Cell-Mediated Class-Switched B Cell Responses | Joo H, Li DP, Dullaers M, Kim TW, Duluc D, Upchurch K, Xue YM, Zurawski S, Le Grand R, Liu YJ, Kuroda M, Zurawski G, Oh S | | | | | Musculoskeletal Pain in Patients With Chronic Myeloid Leukemia After Discontinuation of Imatinib: A Tyrosine Kinase Inhibitor Withdrawal Syndrome? Reply | Rousselot P, Charbonnier A, Cony-Makhoul P, Agape P, Nicolini FE, Varet B, Gardembas M, Etienne G, Rea D, Roy L, Escoffre-Barbe M, Guerci-Bresler A, Tulliez M, Prost S, Spentchian M, Cayuela JM, Reiffers J, Chomel JC, Turhan A, Guilhot J, Guilhot F, Mahon FX | | | | | GENE THERAPY Primed for take-off | | | | | | Parallel Assessment of Globin Lentiviral Transfer in Induced Pluripotent Stem Cells and Adult Hematopoietic Stem Cells Derived from the Same Transplanted beta-Thalassemia Patient | Tubsuwan A, Abed S, Deichmann A, Kardel MD, Bartholoma C, Cheung A, Negre O, Kadri Z, Fucharoen S, von Kalle C, Payen E, Chretien S, Schmidt M, Eaves CJ, Leboulch P, Maouche-Chretien L | | | | | Arrayed lentiviral barcoding for quantification analysis of hematopoietic dynamics | Grosselin J, Sii-Felice K, Payen E, Chretien S, Roux DT, Leboulch P | | | | | LENTIVIRUS VECTORS IN beta-THALASSEMIA | Payen E, Colomb C, Negre O, Beuzard Y, Hehir K, Leboulch P | | | | | Stem Cell Factor-Displaying Simian Immunodeficiency Viral Vectors Together with a Low Conditioning Regimen Allow for Long-Term Engraftment of Gene-Marked Autologous Hematopoietic Stem Cells in Macaques | Verhoeyen E, Relouzat F, Cambot M, Costa C, Negre D, Legrand F, Joubert C, Le Grand R, Cosset FL, Leboulch P, Dubart-Kupperschmitt A, Prost S | | | | | BET bromodomain inhibition rescues erythropoietin differentiation of human erythroleukemia cell line UT7 | Goupille O, Penglong T, Lefevre C, Granger M, Kadri Z, Fucharoen S, Maouche-Chretien L, Leboulch P, Chretien S | Biochem. Biophys. Res. Commun., 2012 | | | | Advances in stem cell transplantation and gene therapy in the beta-hemoglobinopathies | | Hematol.-Am. Soc. Hematol. Educ. Program, 2012 | |
|