| Long Term Gene Expression in Human Induced Pluripotent Stem Cells and Cerebral Organoids to Model a Neurodegenerative Disease | Nassor F, Jarray R, Maïza A, Papy-Garcia D, Pavoni S, Deslys JP, Yates F | | | | Neuropathology of iatrogenic Creutzfeldt-Jakob disease and immunoassay of French cadaver-sourced growth hormone batches suggest possible transmission of tauopathy and long incubation periods for the transmission of Abeta pathology. | Duyckaerts C, Sazdovitch V, Ando K, Seilhean D, Privat N, Yilmaz Z, Peckeu L, Amar E, Comoy E, Maceski A, Lehmann S, Brion JP, Brandel JP, Haïk S | | | | Small-molecule induction of Abeta-42 peptide production in human cerebral organoids to model Alzheimer's disease associated phenotypes | Pavoni S, Jarray R, Nassor F, Guyot AC, Cottin S, Rontard J, Mikol J, Mabondzo A, Deslys JP, Yates F | | | | Unexpected prion phenotypes in experimentally transfused animals: predictive models for humans? | Comoy E, Mikol J, Deslys JP | | | | Differential overexpression of SERPINA3 in human prion diseases. | Vanni S, Moda F, Zattoni M, Bistaffa E, De Cecco E, Rossi M, Giaccone G, Tagliavini F, Haïk S, Deslys JP, Zanusso G, Ironside JW, Ferrer I, Kovacs GG, Legname G | | | | Contrast-enhanced MR microscopy of amyloid plaques in five mouse models of amyloidosis and in human Alzheimer's disease brains | Dudeffant C, Vandesquille M, Herbert K, Garin CM, Alves S, Blanchard V, Comoy EE, Petit,F, Dhenain M | | | | Experimental transfusion of variant CJD-infected blood reveals previously uncharacterised prion disorder in mice and macaque | Comoy EE, Mikol J, Jaffre N, Lebon V, Levavasseur E, Streichenberger N, Sumian C, Perret-Liaudet A, Eloit M, Andreoletti O, Haik, S, Hantraye, P, Deslys, JP | | | | Induced pluripotent stem cell generation from a man carrying a complex chromosomal rearrangement as a genetic model for infertility studies | Mouka A, Izard V, Tachdjian G, Brisset S, Yates F, Mayeur A, Drevillon L, Jarray R, Leboulch P, Maouche-Chretien L, Tosca L | | | | Detection and partial discrimination of atypical and classical bovine spongiform encephalopathies in cattle and primates using real-time quaking-induced conversion assay | Levavasseur E, Biacabe AG, Comoy E, Culeux A, Grznarova K, Privat N, Simoneau S, Flan B, Sazdovitch V, Seilhean D, Baron T, Haik S | | | | Forced extinction of CD24 stem-like breast cancer marker alone promotes radiation resistance through the control of oxidative stress | Bensimon J, Biard D, Paget V, Goislard M, Morel-Altmeyer S, Konge J, Chevillard S, Lebeau J | | | | Validation of an air-liquid interface toxicological set-up using Cu, Pd, and Ag well-characterized nanostructured aggregates and spheres | Svensson CR, Ameer SS, Ludvigsson L, Ali N, Alhamdow A, Messing ME, Pagels J, Gudmundsson A, Bohgard M, Sanfins E, Karedal M, Broberg K, Rissler J | | | | New insights in the transfusional risk assessment of variant Creutzfeldt-Jakob Disease: Transfusional transmission of vCJD prions in the absence of detectable abnormal prion protein | Comoy EE, Jaffre N, Mikol J, Durand V, Lescoutra-Etchegaray N, Levavasseur E, Streichenberger N, Haik S, Deslys JP | | | | Transmission of prions to non human-primates: Implications for human populations | | | | | Non-equivalent binding sites for Abeta1-40 on PrP determine the oligomerisation pathway | Grznarova K, Torrent J, Munoz-Montesino C, Nasica J, Derreumaux P, Beringue V, Deslys JP, Rezaei H | | | | A novel approach combining 3D human cell culture and 3D microscopy to assess prion infectivity | Nassor F, Pavoni S, Jarray R, Jouy D, Cottin S, Rontard J, Comoy EE, BIARD DSF, Yates F, Deslys JP | | | | Impact of Astroglial Connexins on Modafinil Pharmacological Properties | Duchene A, Perier M, Zhao Y, Liu XH, Thomasson J, Chauveau F, Pierard C, Lagarde D, Picoli C, Jeanson T, Mouthon F, Dauvilliers Y, Giaume C, Lin JS, Charveriat M | | | | Translesion synthesis mechanisms depend on the nature of DNA damage in UV-irradiated human cells | Quinet A, Martins DJ, Vessoni AT, Biard D, Sarasin A, Stary A, Menck CFM | | | | A balanced pyrimidine pool is required for optimal Chk1 activation to prevent ultrafine anaphase bridge formation | Gemble S, Buhagiar-Labarchede G, Onclercq-Delic R, Biard D, Lambert S, Amor-Gueret M | | | | Detection of exosomal prions in blood by immunochemistry techniques | Properzi F, Logozzi M, Abdel-Haq H, Federici C, Lugini L, Azzarito T, Cristofaro I, di Sevo D, Ferroni E, Cardone F, Venditti M, Colone M, Comoy E, Durand V, Fais S, Pocchiari M | | | | Interaction with OGG1 is required for efficient recruitment of XRCC1 to base excision repair and maintenance of genetic stability after exposure to oxidative stress | Campalans A, Moritz E, Kortulewski T, Biard D, Epe B, Radicella JP | | | | Blood reference materials from macaques infected with variant Creutzfeldt-Jakob disease agent | McDowell KL, Nag N, Franco Z, Bu M, Piccardo P, Cervenak J, Deslys JP, Comoy E, Asher DM, Gregori L | | | | The prion protein is critical for DNA repair and cell survival after genotoxic stress | Bravard A, Auvre F, Fantini D, Bernardino-Sgherri J, Sissoeff L, Daynac M, Xu Z, Etienne O, Dehen C, Comoy E, Boussin FD, Tell G, Deslys JP, Radicella JP | | | | Creating conditions for the success of the French industrial advanced therapy sector | Lirsac PN, Blin O, Magalon J, Angot P, de Barbeyrac E, Bilbault P, Bourg E, Damour O, Faure P, Ferry N, Garbil B, Larghero J, Nguon M, Pattou F, Thumelin S, Yates F | | | | Uncommon prion disease induced in macaque ten years after scrapie inoculation | Mikol J, Luccantoni-Freire S, Correia E, Lescoutra-Etchegaray N, Durand V, Dehen C, Deslys JP, Comoy E | Neuropathol. Appl. Neurobiol., 2015 | | | PARP-2 depletion results in lower radiation cell survival but cell line-specific differences in poly(ADP-ribose) levels | Boudra MT, Bolin C, Chiker S, Fouquin A, Zaremba T, Vaslin L, Biard D, Cordelieres FP, Megnin-Chanet F, Favaudon V, Fernet M, Pennaneach V, Hall J | Cell. Mol. Life Sci., 2015 | | | Synthetic Scrapie Infectivity: Interaction between Recombinant PrP and Scrapie Brain-Derived RNA | Simoneau S, Thomzig A, Ruchoux MM, Vignier N, Daus ML, Poleggi A, Lebon P, Freire S, Durand V, Graziano S, Galeno R, Cardone F, Comoy E, Pocchiari M, Beekes M, Deslys JP, Fournier JG | | | | Transmission of prions to primates after extended silent incubation periods: Implications for BSE and scrapie risk assessment in human populations | Comoy E, Mikol J, Durand V, Luccantoni S, Correia E, Lescoutra N, Dehen C, Deslys JP | | | | Transmission of CWD to non-human primates: Interim results of a 6 year risk assessment study on the transmissibility to humans | Mussil B, Motzkus D, Hesse G, Borchert S, Schiller B, Stahl-Hennig C, Schulz-Schaeffer W, Beekes M, Daus M, Schatzl HM, Dudas S, Yang JM, Deslys JP, Czub S | | | | Reversal of mitochondrial defects with CSB-dependent serine protease inhibitors in patient cells of the progeroid Cockayne syndrome | Chatre L, BIARD DSF, Sarasin A, Ricchetti M | Proc. Natl. Acad. Sci. U. S. A., 2015 | | | Transmission of scrapie prions to primate after an extended silent incubation period | Comoy EE, Mikol J, Luccantoni-Freire S, Correia E, Lescoutra-Etchegaray N, Durand V, Dehen C, Andreoletti O, Casalone C, Richt JA, Greenlee JJ, Baron T, Benestad SL, Brown P, Deslys JP | | |
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