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The François Jacob Institute of Biology brings together five departments and three services
The last two years in scientific news
The efficacy of a gene therapy developed at the François Jacob Institute of Biology and Harvard University has been demonstrated in phase I/II clinical trials.
Researchers at IRCM have shown that certain mechanisms involved in DNA repair are influenced by the intramolecular and intranuclear spatial organization of the macromolecule.
The results of a study performed by a research team at MIRCen suggest that the protein DCLK3 plays a key role in transcription regulation, and its deficit in Huntington's disease a key role in neurodegeneration.
Researchers from MIRCen have brought to light a reduction in the amount of an amyloid beta peptide associated with Alzheimer's disease in the plasma of a primate model during the summer season.
Neurofibrillary tangles are large aggregates of tau protein found in the neurons of people with Alzheimer's disease. Historically, they have been thought to be at least partially responsible for the pathology. However, the results of a study performed by researchers at MIRCen (François Jacob Institute of Biology/CEA) suggest to the contrary that neurofibrillary tangles may be protective.
What is the genetic "signature" of domesticated animals? Researchers from the François Jacob Institute of Biology participated in a study to shed light on that very question.
Researchers from NeuroSpin (Frédéric-Joliot Institute/CEA) and MIRCen (François Jacob Institute of Biology/CEA) recently developed an MRI-guided focused ultrasound system that increases, temporarily and locally, cerebral vascular permeability in non-human primates. The system could improve the delivery of medicines to the brain.
A team from the Innovative Therapies Unit (STI) has discovered a molecular mechanism that regulates the balance between white and brown fat. Their work defines a novel category of potential targets in the quest to control fat mass.
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.