Leader
Alain PRUVOST
33 1 69 08 13 12
alain.pruvost@cea.fr
Permanent staff
Aurélie Ghettas-Messager, Technician
Frédéric Théodoro, Technician
This platform is implanted in the Pharmacology and Immunoanalysis unit (SPI); it comprises 5 liquid chromatography instruments together with mass spectrometers triple quadrupole analyzers (UPLC-MS/MS). SMArt-MS can access if needed to the high-resolution instruments of MetaboHUB platform. Human resources of the platform are composed of a CEA engineer, two CEA technicians and non-statutory personnel.
Our missions are:
- Development and validation of quantitative bioanalysis methods by LC-MS/MS of small molecules in biological fluids and achievement of the analyzes using these methods
- The realization of metabolism and pharmacokinetic pilot studies (early ADME-DMPK)
- The training of contractual staff using the devices assigned to the platform.
Photos: A.Pruvost
SMArt-MS performs these activities for the Laboratory of Drug Metabolism Research (SPI), other CEA laboratories, LabEx LERMIT which SPI is part and external partners.
SMArt-MS present partners: