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The François Jacob Institute of Biology brings together five departments and three services
The last two years in scientific news
The facilities of CRC MIRCen are dedicated to the exploration and validation of concepts and the preclinical evaluation of new treatment strategies in the domains of gene, cell and drug-based therapies, principally for neurodegenerative diseases.
This platform offers methods, equipment and expertise in biochemistry, cell culture and molecular biology. In addition, it has expertise in the development of AAV virus and lentivirus vectors for the development of disease models and the evaluation of new avenues of treatment.
This platform can be used to develop relevant animal models for diseases, particularly those involving the administration of viral vectors according to experimental procedures (anesthesia, recovery etc.) validated in nonhuman primates and rodents (rats, mice). Also to test new treatments based on the injection of viral vectors or cell grafts.
This platform offers a battery of motor and cognitive tests for rodents and nonhuman primates. These tests can be used to validate animal models of human diseases and evaluate the efficacy of new treatments.
The imaging platform provides equipment and expertise in the imaging of the central nervous system by nuclear magnetic resonance (NMR),positron emission tomography (PET) and optical imaging.
This platform offers methodologies, equipment and expertise of more than 20 years for the selection and engineering of nucleic acid aptamers (DNA, RNA or nuclease resistant chemistry).
The immunohistochemistry and anatomopathology platforms are equipped according to highest technical standards with biosecurity levels A1 and A3. It provides macroscopic, histopathologic and molecular analysis on rodents and non-human primates.
The Image Processing Platform is responsible for the two- and three-dimensional processing of data generated by histology or imaging in vivo and for the quantitative and statistical analysis of results.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.