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Fundamental Research Division
The DRF at the CEA assemble approximately 6,000 scientists since January 2016.
A team from the IBS (CEA-CNRS-Université Joseph Fourrier) has published in Nature the full three-dimensional structure of a serotonin receptor. This is a first for mammals.
An international collaboration led by INRA and the CEA-IG (Genoscope) has published the first reference sequence of a chromosome from wheat. This is a decisive step towards sequencing its entire genome.
An international consortium involving teams from the CEA-IG has developed a new method for analyzing metagenomes. This method has been successfully applied to intestinal microflora, revealing hundreds of previously unknown species.
The rapid industrial success of carbon nanotubes raises questions about their impact on health and the environment. Researchers from the CEA and CNRS have developed a method to monitor these particles in the body, followed by observing their distribution after lung contamination. This study was published in ACS Nano.
By exploiting a large database of psychometric data and brain imaging, the Neurofunctional Imaging Group from Bordeaux has shown that the location of the brain’s language areas is independent of being right- or left-handed ... except for a very small fraction of left-handed people. This work was published in PLoS One on June 30, 2014.
Researchers at the Institut Pasteur, the CEA-IRTSV and the CNRS have shown that the direct environment of stem cells influences the fate of their offspring. According to the tension exerted on these cells types of in division, they can preferentially produce two new stem cells, or a stem cell and a specialized cell, or even two specialized cells.
Researchers from the CEA-IBITECS in collaboration with a team from the University of Strasbourg (UDS) have developed new reagents known as “chelating azides”, which can rapidly and selectively couple to any compound equipped with an alkyne group. The reaction can take place in any environment, including within a cell.
A team from the CEA-IBITECS participated in the identification of a novel role for an enzyme, the protease MMP-12, in the immune response to viral infection. The researchers developed an inhibitor of MMP-12, which enhances the immune response in a rodent model. This work, opens the way for the development of new antiviral therapies.
A French consortium, coordinated by INRA and involving the CEA (Genoscope), the CNRS and the Ecoles Normales Supérieures of Paris and Lyon, has sequenced and analyzed the genome of the rainbow trout . The result challenges a classic hypothesis in genetics.
DBV Technologies, creator of the Viaskin® patch for allergy treatment, has signed a collaborative agreement with the Centre National de Génotypage of the CEA-IG, to understand the epigenetic mechanisms of this treatment.
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.