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Fundamental Research Division
The DRF at the CEA assemble approximately 6,000 scientists since January 2016.
Development of a novel therapy that targets stem cells responsible for chronic myeloid leukemia (CML). The first treated patients no longer present a detectable disease more than 5 years after stopping this new treatment, which represents a solid hope for a lasting recovery.
A team from the CEA-IBITECS has participated in the development of a new isotope labeling process to accelerate in vivo studies of drug candidates. The original and unprecedented mechanism of this process was elucidated by computer modeling.
Researchers from the CEA-IRTSV and their partners have revised our understanding of the cellular mechanisms behind the impressive photosynthetic capacity of the unicellular marine organisms known as diatoms. They discovered an unexpected interaction between photosynthesis and respiration.
Cyanobacteria, which use light as a source of energy during photosynthesis, also need to know how to protect themselves from it. Researchers have uncovered a unique mechanism of photoprotection that opens new perspectives for synthetic biology and the production of biomolecules of industrial interest.
A team from the CEA-IBITECS located at the Musée de l'Homme has just determined the complete mitochondrial genome of a steppe bison specimen from a bone fragment dating back 19,000 years, found in the Trois-Frères cave (Ariège).
Proteins that are supposed to be the guardians of neuronal cytoskeletons turn out to play a role in the establishment of brain connections. This discovery from the CEA-IRTSV and INSERM, made in a rodent model, has potential applications in psychiatry.
A special issue of the journal Science features the first results from the Tara Oceans expedition with five publications, in which the CEA-IG participated.
Research teams from INRA and the CEA have just sequenced for the first time the genome of the pedunculate oak tree, which is widely distributed throughout the northern hemisphere. This work will improve our understanding of the adaptive mechanisms of trees to environmental variations, and will thus provide elements that can be used to anticipate their responses to climate change.
Following the discovery of a protein structure that makes sodium transport across bacterial membranes possible, a team of Russian, German and French (IBS) scientists has developed a potential new tool for optogenetics. The latter is a field of research at the crossroads of optics and genetics.
Certain mobile DNA sequences shape genomes and are maintained over the course of generations. How is this explained? The interaction between two proteins, which is essential for their integration into a specific area of the yeast genome, has been identified. This finding has interesting implications for gene therapy.
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.