How novel imaging techniques will revolutionize life, environmental and material sciences
Coupling imaging and spectroscopic technologies with real-time characterization techniques, based on energy/intensity measurements with electromagnetic, optical, acoustic or vibration excitations or chemistry modifications, represents a major step change in materials analysis. Multi-sensor hyperspectral imaging consists of taking measurements in operando conditions using this coupled image acquisition approach.
Leti is currently addressing the following research topics in this field:
- Monitoring the behavior of various macromolecular species in key steps of a cell’s life
- Developing compact sensors/imagers for multi-spectral bands (from IR to UV)
- Capturing the body/brain signals, with discriminating noise filtering, for therapeutic purposes in the case of neurological diseases
- Performing multimodal, multiscale in-situ/operando characterizations of advanced materials to reveal structural, compositional and functional features from the µm-scale down to the nm level. Recent examples are Surface-Enhanced Raman Scattering (SERS), Raman imaging/scanning electron (RISE) microscopy in 3D-FIB-SEM, and surface imaging techniques (ToF-SIMS, PEEM, Auger and scanning probes)
- Developing portable CT-scanner and portable ultralow-field magnetic resonance imaging (MRI) systems, using new technologies of emission, detection, or new geometries (in the same way that lens-free on-chip imaging facilitates novel microscopy applications)
- Monitoring fabrication/retail processes with on-line quality and safety controls.
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Correlation of imaging (X-ray tomography) with spectroscopy (3D-FIB-TOF-SIM) on the same object
Photos ©CEA
Referenced publications in our annual research reports:
Ujwol Palanchoke, Salim Boutami, Serge Gidon ‘Tailoring multi spectral absorption using CMOS compatible MIM resonator’, Optro 2012
B. Delplanque, S. Pocas, S. Boutami, J. L. Ouvrier Buffet, S. Becker, C. Vialle, V. Goudon, J. J. Yon, A.Hamelin, S. Martin, W. Rabaud, ‘A multispectral uncooled infrared imager for passive remote gas detection and identification’, 12th International Symposium on Protection against Chemical and Biological Warfare Agents, 2016.
3D correlative morphological and elemental characterization of materials at the deep submicrometre scale A. Priebe, G. Goret, P. Bleuet, G. Audoit, J Laurencin, JP Barnes. JOURNAL OF MICROSCOPY 264 (2016) 2 pp 247-251.
Doping efficiency of single and randomly stacked bilayer graphene by iodine adsorption H. Kim, O. Renault, A. Tyurnina, J-P Simonato, D. Rouchon, Appl. Phys. Lett. 105 (2016) 011605.
Fast and robust identification of single bacteria in environmental matrices by Raman spectroscopy J-C Baritaux, E. Schultz, A-G Bourdat, P Laurent, J-M Dinten, A-C. Simon, I Espagnon, Proc. SPIE 9328 Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XIII (2015)