Pr Sebire’s research focuses on stroke and infectious/inflammatory aggressions occurring in the developing brain and responsible for severe handicaps, ie cerebral palsy, learning disabilities and behaviourial disorders such as autism. Through a combination of clinical and experimental approaches, his team has shown that prenatal exposure to bacterial components induces cerebral lesions, through cytokines' release, and predisposes to circulatory defects which occur immediately after birth.
​ Based on this vision, one of the main strength of his lab is to build pertinent preclinical animal models inspired from patients’ reality to mimic the complex scenarios underlying kids’ brain diseases from obscure origin, and take advantage of these models to further understand their mechanisms, and to uncover new diagnostic markers and neuroprotective treatments

https://www.youtube.com/watch?v=A7h7Lk9dQQs​

​​L'accès au site CEA nécéssite un laisser passer. ​​Contact ​: ​​Nadia Alfaidy-Benharouga​​​​​

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