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To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
All the news of the Institute of life sciences Frédéric Joliot
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A Research Team in psychiatry at CEA-NeuroSpin, in collaboration with the Mondor Institute for Biomedical Research (INSERM) and Henri-Mondor University Hospitals, AP-HP, has shown that a genetic variant associated with multiple psychiatric disorders alters a network. prefronto-limbic, which would increase the risk of developing schizophrenia or bipolar disorder. The results of this study are published online October 2, 2017 in the Journal of Neuroscience.
Researchers from BIAM (CEA / Cadarache), in collaboration with a Research Team of the Frédéric Joliot Institute (I2BC @ Saclay), the BGE laboratory and ESFR (Grenoble) have discovered an enzyme that allows microalgae to transform certain from their fatty acids to hydrocarbons using only light energy. Published on 01/09/2017 in Science, this major discovery was the subject of a press release.
Researchers from SB2SM and four other Research Teams (Yale University, Arizona State University, Argonne National Lab and Institute for High Performance Computing, Singapore) have identified a photosynthesis mechanism that protects plants from excess light energy . These results could contribute to the development of more efficient energy systems in new solar technologies.
Deriving from a collaboration between the SHFJ and MIRCen, this work presents a new and original method of quantification of positron emission tomography (PET) images adapted to hybrid PET / MRI cameras, developed by combining the expertise of MIRCen in MRI preclinical and SHFJ expertise in preclinical PET.
As part of an international collaboration, researchers from LI2D (SPI / Marcoule) and University of Warwick have highlighted the long-term benefits of the association between different marine microorganisms. The study published in Nature Microbiology shows that, contrary to what was admitted up to now, these microorganisms are in equilibrium and not in competition for micronutrients, because they form a complementary ecosystem.
In an article published the 10th of May in Nature Communications, some Research Teams of the Frédéric Joliot Institute (SBIGeM, SPI) discovered that a new histone variant called H2A.J accumulates in human fibroblasts in senescence.
A collaboration between researchers of the Yamanashi University (Japan) and the CEA showed that it is possible to characterize liver lesions from their elastic properties estimated virtually from MRI measurements of the molecular diffusion of the water. The MRI is thus an interesting option to succeed the conventional MRI elastography used in these exams, the latter with defects (low resolution images, heavy implementation). This work was published in the journal Radiology on June 12, 2017.
A Research Team of the SHFJ (LDM-TEP) has just developed an innovative radiopharmaceutical for lymphoproliferative diseases, [18F] Fludarabine.
A SIMOPRO Research Team has characterized a green mamba venom toxin, mambaquetine, which is proving to be a very promising therapeutic candidate for the fight against polycystic kidney disease, a genetic disorder that causes cysts in kidneys
The free project PIWS is developed by NeuroSpin. It allows to assemble and serve the data of major European / international projects in population imaging for big-data analyzes. PIWS relies on CubicWeb, a semantic web software developed by the French company Logilab.
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.