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To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
All the news of the Institute of life sciences Frédéric Joliot
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In a study conducted by the Neurofunctional Imaging Group (GIN, NeuroSpin, Bordeaux), a classification technique by Support Vector Machine (SVM) , a supervised learning technique, is used to predict the different hemispheric dominance patterns for language and to highlight the existence of very rare patterns in some healthy individuals.
A Research Team from the SHFJ (IMIV) highlights, through a preclinical model of exposure to alcohol, an immediate and persistent neuro-immune response, several months after the initial exposure of alcohol. These results confirm the occurrence of brain damage that may play a key role in the neurological deficits reported in teenagers who like "binge-drinking", that is to say an excessive consumption of alcohol over a very short time.
A Research Team of the SCBM (Frédéric Joliot Institute), in collaboration with the SIMOPRO (Frédéric Joliot Institute), Strasbourg University and the start-up Syndivia, has just discovered a new chemical reaction allowing both to bind and to cleave molecules in biological media ("click and release" reaction).
An LSOD Research Team (I2BC@Saclay), in collaboration with a Research Team from Mar del Plata University (Argentina), has been able to characterize for the first time a NO-Synthase of plants. Researchers have shown that NO-Synthase from Ostreococcus tauri (pico plankton from the Thau lagoon) produces very large amounts of NO compared to human NO-synthases. However, terrestrial plants do not have NO-synthases and the biological role of this enzyme remains unknown.
For the first time, an animal model expresses the two biological characteristics of Alzheimer's disease. Researchers from MIRCen (François Jacob Institute), SPI (LEMM), Inserm, Universities Paris-Sud and Paris-Descartes and CNRS have developed an animal model that reproduces the progression of the human disease.
Two Research Teams led by Odette Prat of the Institute of Biosciences and Biotechnologies (BIAM) and Jean Armengaud of the Frédéric Joliot Institute (LI2D, Marcoule) have joined forces thanks to an ANR funding to deepen knowledge of the importance of the nature of protein crowns on the cellular impact of nanoparticles. The results from their three recent publications reveal a new concept: "the protein interactome applied to the corona of nanoparticles".
A Research Team in psychiatry at CEA-NeuroSpin, in collaboration with the Mondor Institute for Biomedical Research (INSERM) and Henri-Mondor University Hospitals, AP-HP, has shown that a genetic variant associated with multiple psychiatric disorders alters a network. prefronto-limbic, which would increase the risk of developing schizophrenia or bipolar disorder. The results of this study are published online October 2, 2017 in the Journal of Neuroscience.
Researchers from BIAM (CEA / Cadarache), in collaboration with a Research Team of the Frédéric Joliot Institute (I2BC @ Saclay), the BGE laboratory and ESFR (Grenoble) have discovered an enzyme that allows microalgae to transform certain from their fatty acids to hydrocarbons using only light energy. Published on 01/09/2017 in Science, this major discovery was the subject of a press release.
Researchers from SB2SM and four other Research Teams (Yale University, Arizona State University, Argonne National Lab and Institute for High Performance Computing, Singapore) have identified a photosynthesis mechanism that protects plants from excess light energy . These results could contribute to the development of more efficient energy systems in new solar technologies.
Deriving from a collaboration between the SHFJ and MIRCen, this work presents a new and original method of quantification of positron emission tomography (PET) images adapted to hybrid PET / MRI cameras, developed by combining the expertise of MIRCen in MRI preclinical and SHFJ expertise in preclinical PET.
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CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.